Smart Library
Faceted search across all 5 registries. Filter by registry type, evidence level, or safety domain.
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Evidence level
Showing 6 of 780 entries. Refine via URL query params.
Conditions
6Thumb Carpometacarpal (CMC-1) Osteoarthritis
Tier BOff-label use with RCT evidence: single-session leech therapy reduces pain and improves function in CMC-1 (basal thumb) OA at 8 weeks.
Lateral Epicondylitis (Tennis Elbow)
Tier BOff-label use with two RCTs showing significant pain reduction at 7-12 weeks compared to topical NSAID and conventional physiotherapy.
Plantar Fasciitis
Tier BOff-label use with one RCT showing significant heel pain reduction at 6 weeks compared to conservative care.
Chronic Venous Insufficiency (CEAP C3-C5)
Tier BOff-label use with controlled trial evidence for symptomatic improvement in venous claudication, leg heaviness, and edema in CEAP C3-C5 stages.
Chronic Rhinosinusitis
Tier BOff-label use with one RCT showing symptom and SNOT-22 score improvement at 4 weeks in non-polypoid chronic sinusitis.
Lumbar Radiculopathy (Sciatica)
Tier CInvestigational use for lumbar radiculopathy; the closest randomized evidence is in chronic low back pain (Hohmann 2018, n=44), not radicular pain.