American Society of Hirudotherapy

Nosocomial Infections from Medicinal Leeches — Epidemiology and Prevention

First systematic investigation of Aeromonas infections following clinical leech use

Last Updated: June 18, 2026Reviewed by: ASH Editorial Board
Research article — evidence reviewArticle reference
Evidence: Research reportSafety & Infection ControlSartor C et al. · Clinical Infectious Diseases, 2002

Abstract

The manner in which leeches are maintained before they are used for therapy has not been studied as a factor contributing to nosocomial infections. A 5-year retrospective survey of Aeromonas hydrophila nosocomial infections at a hospital in Marseille, France, revealed infections in 5 (4.1%) of an estimated 122 patients treated with leeches in the Hand Surgery Unit and 2 (2.4%) of an estimated 85 patients treated with leeches in other hospital units. The retrospective survey showed that the Hand Surgery Unit was the only unit that had its own aquarium for maintaining leeches; this aquarium was filled with tap water contaminated with Aeromonas species and was not regularly disinfected or cleaned. Leeches used in other units were maintained in noncarbonated water in a transport device. Use of leeches kept in aquariums that are filled with tap water and not disinfected or cleaned regularly may be linked to A. hydrophila infections.

Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.

Publication typeJournal Article
Indexed MeSH termsAeromonas hydrophilaAnimalsCross InfectionGram-Negative Bacterial InfectionsHumansLeechesLeeching

Summary

Systematic investigation of nosocomial infections caused by Aeromonas species following medicinal leech therapy. Characterized the clinical presentation, microbiological profile, and risk factors for infection, establishing the evidence base for routine antibiotic prophylaxis during leech therapy.

Why This Matters for Hirudotherapy

Foundational safety study that defined the Aeromonas infection risk and drove adoption of prophylactic antibiotic protocols. Directly informs current clinical guidelines requiring fluoroquinolone prophylaxis during leech therapy, now standard of care in microsurgery units.

Citation

Nosocomial Infections with Aeromonas hydrophila from Leeches

Sartor C et al. · Clinical Infectious Diseases, 2002

Added to ASH library: March 18, 2026 · Site last updated: June 18, 2026

This website provides educational information and does not constitute medical advice, diagnosis, or treatment recommendations. Medicinal leech therapy carries clinically meaningful risks and should be performed only by qualified clinicians under institutionally approved protocols. FDA 510(k) clearance for medicinal leeches is limited to specific indications; investigational and off-label discussions are labeled accordingly. For patient-specific guidance, consult a qualified healthcare provider.