Medical management of postpartum hemorrhage: An update.
Review published in Seminars in perinatology (2018)
Abstract
Obstetrical hemorrhage is the most common cause of maternal mortality worldwide. Together with adequate surgical control and judicious transfusion of blood products, the use of pharmacological agents (e.g., tranexamic acid) and clotting factor concentrates (e.g., fibrinogen concentrates and prothrombin complex concentrates) results in improved hemostasis and decreased bleeding-associated mortality. Guidance in the administration of these agents with the use of viscoelastic testing will likely become standard of care in the near future.
Abstract sourced from PubMed (NCBI) for the cited record. See the original publication for the authoritative version.
Summary
Obstetrical hemorrhage is the most common cause of maternal mortality worldwide. Together with adequate surgical control and judicious transfusion of blood products, the use of pharmacological agents (e.g., tranexamic acid) and clotting factor concentrates (e.g., fibrinogen concentrates and prothrombin complex concentrates) results in improved hemostasis and decreased bleeding-associated mortality.
Why This Matters for Hirudotherapy
Contributes to the clinical evidence base on hemostasis, bleeding, and transfusion relevant to hirudotherapy and anticoagulant safety.
Citation
Medical management of postpartum hemorrhage: An update.
Pacheco LD et al. · Seminars in perinatology, 2018
Added to ASH library: May 28, 2026 · Site last updated: June 18, 2026